For weeks, the crew of Scream tried to find a phone voice for the film and finally found Roger Jackson, who does a lot of narration and radio voices in San Francisco.
Kevin Patrick Walls, who makes a small appearance in Scream as Steve Orith, happened to be one of the last contendors for the part of Billy Loomis, which was given to Skeet Ulrich.
Joseph Whipp, who played a police officer in Wes Craven's A Nightmare On Elm Street (1984), makes an appearance as Sheriff Burke.
Henry Winkler, best known as Fonzie from the TV-series Happy Days (1974), plays Principal Himbry. "Henry is represented by my agent," says Wes Craven. "We met about a year ago, and I was really astonished when he said he wanted to be in this film. He played it with a sort of a malicious glee, which I thought was really amazing."
Lisa Beach, the casting director of Scream, makes a cameo as a news reporter on television. She quotes, "Casey Becker and her boyfriend Steven Orith were found dead late last night by the girl's parents."
W. Earl Brown, who played a morgue attendant in Wes Craven's New Nightmare (1994) and a police officer in A Vampire in Brooklyn (1995), gained 20 pounds for the role of Kenny, the cameraman.
Linda Blair, who starred in The Exorcist (1973) and Wes Craven's TV-movie Stranger in Our House (1978), plays an obnoxious news reporter. She quotes, "How does it feel to be almost brutally butchered? How does it feel? People have a right to know!"
Entertainment Tonight's Lisa Canning appears as a television reporter holding the Scream mask. She quotes, "17-year-old Casey Becker and her boyfriend Steven Orith have already lost their lives. Who's next?"
Scream director Wes Craven makes a quick appearance as the school janitor Fred, wearing the original Freddy Krueger costume from A Nightmare on Elm Street (1984).
Dean Farlow, who was a stuntman on the set of Wes Craven's The Serpent and the Rainbow (1988), played Father Death mostly throughout the film.
Priscilla Pointer, who starred in Carrie (1976), makes a small appearance as Maureen Prescott.